Growth hormone deficiency is a typical medical condition by which the pituitary gland does not produce enough quantity of growth hormone. Growth hormone is a polypeptide hormone of 191 amino acids components. This hormone mainly used for cell reproduction and it helps to stimulate the growth of human body. Growth hormone deficiency (GHD) more commonly found among children than adults. This condition among children is not very rare, 1 out of 6000 new born baby suffers by it. The condition is also responsible for the disease like Turner syndrome and Prader-Willi syndrome. Hypoglycemia and micropenis are more common effects caused by the GHD during infancy. In later stage growth failure can be seen. Although in adults it is rare, yet some common example of GHD in adulthood is lean body mass, poor bone density and other physiological symptoms like loss of physical strength, stamina and musculator. Production of other hormones can be affected due to growth hormone deficiency. Mental condition like depression, poor memory etc can be seen in adults. After puberty the GHD can be seen, but it is rare.
Early treatment can recover the dwarfism condition among child. Growth hormone replacement therapy can improve the GHD condition.
Causes of Growth Hormone Deficiency
Cleft lips and cleft palates are more common among children who are suffering from GHD. GHD may idiopathic during childhood and adult-onset in may cause pituitary tumours.
Some Common reasons of GHD
- Due to the mutation of specific genes.
- Due to the radiation therapy to the head.
- Pituitary apoplexy
- Low blood pressure
- Turner syndrome / Prader-Willi syndrome
- Head injury/surgery known as Acquired growth hormone deficiency.